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A new series of thiazole-hydrazone hybrids for Akt-targeted therapy of non-small cell lung cancer
Turana Orujova, Abdulilah Ece, Gülşen Akalın Çiftçi, Ahmet Özdemir, Mehlika D. Altıntop Drug Development Research, DOI: https://doi.org/10.1002/ddr.22022, (2022). (IF= 5.004) |
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Indane Based Molecular Motors: UV-Switching Increases Number of Isomers
Valeriy P. Shendrikov, Anna S. Alekseeva, Erik F. Kot, Konstantin S. Mineev, Daria S. Tretiakova, Abdulilah Ece and Ivan A. Boldyrev Molecules, DOI: https://doi.org/10.3390/molecules27196716, (2022). (IF= 4.927) |
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Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies
Cem Yamali, Halise Inci Gul, Mehtap Tugrak Sakarya, Begum Nurpelin Saglik, Abdulilah Ece, Goksun Demirel, Merve Nenni, Serkan Levent, Ahmet Cihat Oner Bioorganic Chemistry, DOI: https://doi.org/10.1016/j.bioorg.2022.105822, (2022). (IF= 5.307) |
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Novel urea-thiourea hybrids bearing 1,4-naphthoquinone moiety: Anti-inflammatory activity on mammalian macrophages by regulating intracellular PI3K pathway, and molecular docking study
Cagla Efeoglu, Derya Yetkin, Yahya Nural, Abdulilah Ece, Zeynel Seferoğlu & Furkan Ayaz Journal of Molecular Structure, DOI: https://doi.org/10.1016/j.molstruc.2022.133284, (2022). (IF= 3.841) |
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Epichlorohydrin and tripolyphosphate-crosslinked chitosan–kaolin composite for Auramine O dye removal from aqueous solutions: Experimental study and DFT calculations
Zeynep Mine Şenol, Serap Çetinkaya, Ali Fazıl Yenidünya, Faika Başoğlu-Ünal, Abdulilah Ece International Journal of Biological Macromolecules, DOI: https://doi.org/10.1016/j.ijbiomac.2022.01.008, (2022). (IF= 8.025) |
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New bis-and tetrakis-1, 2, 3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants
Yahya Nural, Sadin Ozdemir, Mustafa Serkan Yalcin, Bunyamin Demir, Hasan Atabey, Zeynel Seferoglu, Abdulilah Ece Bioorganic & Medicinal Chemistry Letters, DOI: https://doi.org/10.1016/j.bmcl.2021.128453, (2022). (IF= 2.94) |
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Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis-1,2,3-triazole Compounds
Yahya Nural, Sadin Ozdemir, Mustafa Serkan Yalcin, Bunyamin Demir, Hasan Atabey, Abdulilah Ece, Zeynel Seferoglu Chemistry Select, DOI: https://doi.org/10.1002/slct.202101148, (2021). (IF= 2.307) |
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Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors
Sercan Askin, Hakan Tahtaci, Cüneyt Türkeş, Yeliz Demir, Abdulilah Ece, Gülşen Akalın Çiftçi, Şükrü Beydemir Bioorganic Chemistry, DOI: 10.1016/j.bioorg.2021.105009, (2021). (IF= 5.307) |
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Novel imidazo[2,1‐b]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: synthesis, in silico, and in vitro evaluation
Faika Başoğlu, Nuray Ulusoy-Güzeldemirci, Gülşen Akalın-Çiftçi, Serap Çetinkaya, Abdulilah Ece Chemical Biology & Drug Design, DOI: 10.1111/cbdd.13896, (2021).(IF= 2.873) |
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Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides
Cem Yamali, Hiroshi Sakagami, Yoshihiro Uesawa, Kota Kurosaki, Keitaro Satoh, Yoshiko Masuda, Satoshi Yokose, Abdulilah Ece, Silvia Bua, Andrea Angeli, Claudiu T Supuran, Halise Inci Gul European Journal of Medicinal Chemistry, DOI: 10.1016/j.ejmech.2021.113351, (2021).(IF= 7.088) |
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Exploring the structural basis of conformational heterogeneity and autoinhibition of human cGMP-specific protein kinase Iα through computational modelling and molecular dynamics simulations
Maryam, Arooma, Rana Rehan Khalid, Sundeep Chaitanya Vedithi, Abdulilah Ece, Suleyman Selim Çınaroğlu, Abdul Rauf Siddiqi, and Tom L. Blundell Computational and Structural Biotechnology Journal, DOI: 10.1016/j.csbj.2020.06.016, (2020).(IF= 6.155) |
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Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti-inflammatory molecule PH46A
Kit Chan, Neil Frankish, Tao Zhang, Abdulilah Ece, Aoife Cannon, Jacintha O'Sullivan, Helen Sheridan Journal of Pharmacy and Pharmacology, DOI: 10.1111/jphp.13269, (2020). (IF= 3.765) |
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E-pharmacophore based virtual screening for identification of dual specific PDE5A and PDE3A inhibitors as potential leads against cardiovascular diseases
Arooma Maryam, Rana Rehan Khalid, Abdul Rauf Siddiqi & Abdulilah Ece Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2020.1748718, (2020).(IF= 5.235) |
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Design, synthesis and molecular modelling studies of some pyrazole derivatives as carbonic anhydrase inhibitors
Yazgı Dizdaroglu, Canan Albay, Tayfun Arslan, Abdulilah Ece, Emir A. Turkoglu, Asiye Efe, Murat Senturk, Claudiu T. Supuran & Deniz Ekinci Journal of Enzyme Inhibition and Medicinal Chemistry, DOI: 10.1080/14756366.2019.1695791, (2019). (IF= 5.756) |
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Synthesis, biological evaluation and in silico modelling studies of 1,3,5-
trisubstituted pyrazoles carrying benzenesulfonamide as potential
anticancer agents and selective cancer-associated hCA IX isoenzyme
inhibitors
Cem Yamali, Halise Inci Gul, Abdulilah Ece, Silvia Bua, Andrea Angeli, Hiroshi Sakagami, Ertan Sahin, Claudiu T.Supuran Bioorganic Chemistry, DOI: 10.1016/j.bioorg.2019.103222, (2019). (IF= 5.307) |
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Towards more effective acetylcholinesterase inhibitors: a comprehensive modelling study based on human acetylcholinesterase protein–drug complex
Abdulilah Ece Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2019.1583606, (2019). (IF= 5.235) |
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An integrated approach towards the development of novel antifungal agents containing thiadiazole: synthesis and a combined similarity search, homology modelling, molecular dynamics and molecular docking study
Mustafa Er, Abdulati Miftah Abounakhla, Hakan Tahtaci, Ali Hasin Bawah, Süleyman Selim Çınaroğlu, Abdurrahman Onaran and Abdulilah Ece Chemistry Central Journal, 12(1), 121, DOI: 10.1186/s13065-018-0485-3, (2018). (IF= 4.215) |
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Synthesis, Structure Elucidation and Biological Activities of Some Novel 4(3H)-Quinazolinones as Anti-Biofilm Agents
Sevda Turk, Sevgi Karakus, Abdulilah Ece, Seyhan Ulusoy, Gulgun Bosgelmez-Tınaz Letters in Drug Design & Discovery, DOI: 10.2174/1570180815666180621101123, (2018). |
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Experimental and theoretical studies on tautomeric structures of a newly synthesized 2,2′(hydrazine-1,2-diylidenebis(propan-1-yl-1-ylidene))diphenol
Tuncay Karakurt, Alaaddin Cukurovali, Nuriye Tuna Subasi, Abdurrahman Onaran, Abdulilah Ece, Sıtkı Eker, Ibrahim Kani Chemical Physics Letters, DOI: 10.1016/j.cplett.2018.01.016, (2018). |
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In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-Substituted Piperazine Moieties
Tunca Gul Altuntas, Nilufer Yilmaz, Abdulilah Ece, Nurten Altanlar, Sureyya Olgen Letters in Drug Design & Discovery, DOI: 10.2174/1570180815666180109161948, (2018). |
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Synthesis, molecular modeling, and biological evaluation of 4-[5-aryl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamides toward acetylcholinesterase, carbonic anhydrase I and II enzymes
Cem Yamali, Halise Inci Gul, Abdulilah Ece, Parham Taslimi, Ilhami Gulcin Chemical Biology & Drug Design, DOI: 10.1111/cbdd.13149, (2017). (IF= 2.817) |
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Design, Synthesis, SAR and Molecular Modeling Studies of
Novel Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives as
Highly Potent Antimicrobial Agents
Hakan Tahtaci, Hatice Karacık, Abdulilah Ece, Mustafa Er and Mine Gül Şeker Molecular Informatics, 1-15, DOI: 10.1002/minf.201700083, (2017).(IF= 4.050) |
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Synthesis, characterization, preliminary SAR and molecular docking study of some novel substituted imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as antifungal agents
Mustafa Er, Buğracan Ergüven, Hakan Tahtaci, Abdurrahman Onaran, Tuncay Karakurt, Abdulilah Ece Medicinal Chemistry Research 26 (3), 615-630, DOI: 10.1007/s00044-017-1782-4, (2017). |
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Synthesis, structural characterization, and antiproliferative/cytotoxic effects of a novel modified poly (maleic anhydride-co-vinyl acetate)/doxorubicin conjugate
Gulderen Karakus, Abdulilah Ece, Ayse Sahin Yaglioglu, Haci Bayram Zengin, Mesut Karahan Polymer Bulletin 74 (6), 2159-2184, DOI: 10.1007/s00289-016-1821-1, (2016). |
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E-Pharmacophore Mapping Combined with Virtual Screening and Molecular Docking to Identify Potent and Selective Inhibitors of P90 Ribosomal S6 Kinase (RSK)
Abdulilah ECE Turkish Journal of Pharmaceutical Sciences . 2016, Vol. 13 Issue 2, p241-247, DOI: 10.4274/tjps.28290, (2016). |
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A computational insight into acetylcholinesterase inhibitory activity of a new lichen depsidone
Abdulilah Ece, Boris Pejin Journal of enzyme inhibition and medicinal chemistry, Vol. 24, No. 8, 1276-1286, DOI: 10.3109/14756366.2014.949256, (2015). (IF= 5.756) |
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Redox pathways of aliskiren based on experimental and computational approach and its voltammetric determination
Deniz Pamuk, İbrahim Hüdai Taşdemir, Abdulilah Ece, Esin Canel, Esma Kılıç Journal of the Brazilian Chemical Society, 24 (8), 1276-1286, DOI: 10.5935/0103-5053.20130162, (2013). |
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A cooperative computational and experimental investigation on electrochemical behavior of metoprolol and its voltammetric determination
Seraceddin Levent Zorluoğlu, İbrahim Hüdai Taşdemir, Abdulilah Ece, Esma Kiliç Canadian Journal of Chemistry, 2013, 91(10): 951-959, 1276-1286, DOI: 10.1139/cjc-2012-0531, (2013). |
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The discovery of potential cyclin A/CDK2 inhibitors: a combination of 3D QSAR pharmacophore modeling, virtual screening, and molecular docking studies
Abdulilah Ece, Fatma Sevin Medicinal Chemistry Research, 22 (12), 5832-5843, DOI: 10.1007/s00044-013-0571-y, (2013). |
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Experimental and theoretical study on the electrochemical behavior of zofenopril and its voltammetric determination
Ibrahim Hudai Tasdemir, Abdulilah Ece, Esma Kilic Current Pharmaceutical Analysis, 8 (4), 339-348, DOI: 10.2174/157341212803341627, (2012). |
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Exploring QSAR on 4-cyclohexylmethoxypyrimidines as antitumor agents for their inhibitory activity of cdk2
Abdulilah Ece, Fatma Sevin Letters in Drug Design & Discovery 7 (9), 625-631, DOI: 10.2174/157018010792929612, (2010). |
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Reaction of Atomic Carbon with Isomeric Cresols
Ilkay Sokmen, Abdulilah Ece, Bulent Duz, Fatma Sevin Letters in Organic Chemistry, 6 (8), 650-653, DOI: 10.2174/157017809790442907, (2009). |
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Application of carbon arc‐generated Mo‐and W‐based catalyst systems to the ROMP of norbornene
Bülent Düz, Can Koray Elbistan, Abdulilah Ece, Fatma Sevin Applied Organometallic Chemistry, 23 (9), 359-364, DOI: 10.1002/aoc.1518, (2009). |
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The first example of tungsten-based carbene generation from WCl 6 and atomic carbon and its use in olefin metathesis
Bülent Düz, Dilek Yüksel, Abdulilah Ece, Fatma Sevin Tetrahedron letters, 47 (29), 5167-5170, DOI: 10.1016/j.tetlet.2006.05.054, (2006). |
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